Free US Shipping for orders $49+
Free US Shipping for orders $49+

Get up to 50% off + FREE shipping with a FREE My Health Account

Free US Shipping for orders $49+

Get up to 50% off + FREE shipping with a FREE My Health Account

Free US Shipping for orders $49+
47193718_m

A Comprehensive List of “Deadly” Nightshades

Nightshade vegetables are notoriously mysterious. And if you’re served anything from the nightshade vegetable list, you have good reason to be wary. Nightshade vegetables can be dangerous to your health. That’s why the term “nightshades” is so apropos. The label implies danger. Foods on the nightshades vegetable list might appear harmless, but some could cause serious health concerns. Did you know foods on the nightshades vegetable list might contribute to the following health issues?

  • Digestive issues
  • Dry mouth
  • Confusion,
  • Vomiting
  • Visual disturbances1

Foods On The Nightshade Vegetables List And Where They Come From

nightshade vegetables | Gundry MD

While you’ll find all sorts of potatoes, tomatoes, and other members of the Solanaceae (aka nightshade) family all over the world, nightshade vegetables are most abundant in tropical climates like that of Latin America. Approximately 50 species of nightshade plants can be found right here in North America.1

Nightshades get their name from the toxic alkaloids found in several of the species.

Now, alkaloids can have certain drug-like effects on people.2 And one of the more well-known toxic alkaloids is nicotine. So you can see why the toxic alkaloids in the foods on this nightshade vegetable list could inspire people throughout history to consider these as evil plants.3

Are You Sensitive to Nightshade Vegetables?

Nightshade Vegetables | Gundry MD

There’s really only one way to answer that question. You’ve simply got to remove nightshades from your diet and see if you feel better. So, let’s dig deeper and discover exactly what nightshades are and how they might affect your health.

The Culprits: Foods on the Nightshade List

  • Eggplant (Fruit)
  • Tomatoes (Fruit)
  • Tomatillo (Fruit)
  • Potatoes (Vegetable)
  • Goji Berries (Fruit)
  • Pimentos (Fruit)
  • Peppers (Bell, Chili, Paprika, Cayenne) (Fruit)
  • Tobacco (Leaf)4

Part of the problem when it comes to nightshades are the natural pesticides found within each plant. These are called glycoalkaloids — and much like lectins, they’re there as a plant’s first line of defense against bugs, viruses, bacteria, animals, and even humans.

In fact, in some cases, glycoalkaloids may cause digestive issues like vomiting, diarrhea, and severe abdominal pain.5

How Do These Toxic Compounds Work Exactly?

nightshade vegetables | Gundry MD

Well, they grip onto cholesterol in your body’s cell membranes. Now, the cholesterol is there to strengthen your cell membranes so they’re less permeable to molecules that may want to pass through and cause damage to the cell.

Without cholesterol, your cell membranes wouldn’t be strong enough to keep out these molecules. It’s the perfect place for glycoalkaloids to strike because once the cholesterol is attacked, your cells could split or leak.6 This can lead to some tough health issues.

Again, the job of glycoalkaloids is to damage your cell membranes.

One of the things to note about glycoalkaloid toxins is that they take your body a long time to process — more than a day in some cases.7 So, if you’re scarfing potatoes (or even “healthy” eggplant) every day, you could end accumulating a hefty helping of this natural toxin.

Are Carrots And Onions Nightshade Vegetables?

nightshade vegetables | Gundry MD

As mentioned above, plants in the Solanaceae family are referred to as nightshades. However, onions are not in the nightshade family. Onions are members of the Liliaceae family. In fact, red and yellow onions are actually varieties of the exact same species: Allium cepa. Carrots are not on the Nightshades vegetable list either. If a recipe calls for the use of peppers, or other nightshade vegetables, try using raw carrots or onions instead.

Are Broccoli And Beets Nightshade Vegetables?

Contrary to popular belief, beets are not on the nightshade vegetable list. Beets belong to the Goosefoot family. Other non-nightshade vegetables in the goosefoot family are spinach and Swiss chard.

And everyone’s favorite cruciferous veggie, broccoli, is also not on the nightshade vegetable list. Colorful fruits and vegetables like blueberries and broccoli are often mistaken for nightshades. But these fruits and veggies are full of antioxidants.

Nightshade Vegetables List (Fruits And Leaves Are On It Too)

Nightshade Vegetables | Gundry MD

Since you now know a bit more about nightshades, let’s go through some of those on the nightshade vegetable list one by one and see what there is to uncover about how potatoes, tomatoes, and their friends can potentially wreak havoc on your system.

1. The Eggplant

Years and years ago, when Europeans came across the eggplant for the first time, they dubbed it “mala insane” — which means mad apple. They surmised the eggplant was part of a species of poisonous plants.

Today, it’s known that eggplants produce two different glycoalkaloids — alpha-solamargine and alpha-solasonine.

These potent glycoalkaloids can be found throughout the eggplant — including in the peel, seeds, and meat. The thing is, eggplant (aka Solanum melongena L.) glycoalkaloids are toxic organic compounds. In two types of Iranian eggplants, a number of arsenic and strychnine-like effects on human health have been recorded, including GI disorders and confusion.8

If you must indulge in eggplant, moderate your portion size, and limit the frequency with which you eat it. And make sure to peel it, de-seed it, and pressure cooking to remove as many of those dangerous compounds as possible.

And, depending on your health, it could be best to talk with your doctor about glycoalkaloids and eggplant consumption and how they might affect your digestive issues.

2. The Tomato

Nightshade Vegetables | Gundry MD

When it comes to tomatoes, you’ll find two types of glycoalkaloids — alpha-tomatine and dehydrotomatine. But, tomatine is a compound that actually includes both tomato glycoalkaloids. Interestingly, you can find tomatine throughout the entire tomato.

Now, tomatine content changes due to the maturity of the plant. For instance, an immature green tomato could consist of approximately 500 mg/kg of tomatine, while red, riper tomatoes might only have about 5 mg/kg of the glycoalkaloid.9

According to the U.S. National Library of Medicine, the following symptoms may occur when you come into too much contact with tomatine:

  • Swelling
  • Redness
  • Pain at mucous membranes
  • Coughing/wheezing
  • Symptoms akin to leaky gut, like nausea, vomiting, and diarrhea10

Again, these potential effects are dependent on how much tomatine you might come into contact with and how sensitive you may be to tomatine, but better safe than sorry.

3. The Potato

Nightshade Vegetables | Gundry MD

Now, not every kind of potato is actually a nightshade. For instance, sweet potatoes and yams are not on the nightshade vegetables list. But for all the others in the potato family, it’s hard to believe they could be dangerous. Potatoes are such a staple of the Western diet.

However, the two glycoalkaloids made in potatoes are alpha-solanine and alpha-chaconine. And of all the glycoalkaloids found in nightshade foods, these are the worst. They happen to be the most toxic.11

In fact, in the most severe cases, consumption of these toxic glycoalkaloids has resulted in serious heart health and mood issues.

There are also reports of people getting glycoalkaloid poisoning from potatoes and experiencing the following symptoms:

  • Gastrointestinal discomfort
  • Vomiting
  • Diarrhea12

In one case, nearly 80 school-aged boys became sick after eating potato lunches. Seventeen of those boys were admitted to the hospital.13 Now, if you’re relatively healthy and your digestive tract is intact, most of these glycoalkaloids won’t be able to find their way into your bloodstream. But, if you consume a larger amount of potatoes, or if you suffer from intestinal permeability, the level of potato glycoalkaloids can build up in your system.

If you must consume potatoes, stay away from potato skins. The skins house the highest content of glycoalkaloids.

And if your potatoes are sprouting or contain odd green spots, you’ll want to get rid of them immediately. Furthermore, peeling your potatoes before you cook them can help reduce the number of glycoalkaloids you might consume. But if the potato tastes bitter, or if it causes a kind of burning sensation in your mouth, spit it out immediately.14

Nightshade Vegetables | Gundry MD4. The Pepper

When it comes to the pepper, there are fewer glycoalkaloids that are found in the fruits’ fellow nightshades. However, capsaicin, the compound responsible for the fruit’s hotness, can present some troubling symptoms. For example, some research indicates capsaicin could have a role in causing severe health concerns. Epidemiological studies have suggested that capsaicin could be linked to an increased risk of gallbladder or stomach issues.15,16

5. The Tobacco Leaf

Nightshade Vegetables | Gundry MD

In 1492, when Christopher Columbus “sailed the ocean blue,” he noticed some of the indigenous people in Mexico and Cuba smoking a strange substance. Turned out, they were smoking tobacco.

Back then, in the mid-sixteenth century, several tobacco species were introduced into Europe from the New World.

From then on, tobacco took over many parts of the world as a powerful drug ingested by way of cigarettes, cigars, and even pipes.17 Of course, you know the ingestion of smoke from tobacco products can cause major diseases and even result in death — the negative effects of tobacco are vast. While cigarette smoking causes chronic conditions that appear at older ages, it can be the culprit of immediate negative health effects too.

The effects of tobacco ingestion can include:
  • Escalated oxidative stress and increased visual signs of aging
  • Reduction of antioxidants and micronutrients in the body
  • Redness, puffiness, and joint discomfort
  • Potential weakened immune system status
  • Changes in your lipid levels
  • Respiratory issues such as coughing, phlegm, and wheezing
  • Addiction
  • Gum health issues
  • Difficulty breathing
  • Degeneration in the eyes
  • Issues with the ability to conceive children18

More About Nicotine in Nightshades

Furthermore, tobacco isn’t the only nightshade that contains nicotine. In fact, several unripe nightshade vegetables contain some nicotine. Of course, the nicotine content is greater in the leaves of the tobacco plant. Many researchers view nicotine as another version of lectins.

In other words, nicotine can act as a plant’s natural defense or pesticide, though scientists aren’t entirely sure just how the drug prevents predators from coming after the plant itself. And, would you believe, the nicotine content in riper nightshades can range anywhere from 2 to 7 micrograms per kg of the food.

Now some researchers have discussed the possibility of nicotine being the reason some people become addicted to nightshade foods. Do you feel like you can’t give these foods up? It could be nicotine.

Brighten Your Day By Eliminating Nightshades Altogether

In the end, if you feel you might have some sort of autoimmune disease or that you’re suffering from a leaky gut, you should try cutting out the foods on the nightshade vegetables list. There are several great replacements for these foods, like avocado, Brussels sprouts, and Jerusalem artichokes.

You might also try adding some digestion supplements to support your gut further.

Also, if you’re wondering if you or someone in your family could be allergic or sensitive to these foods, remove them from your diet and take note of how you feel after having removed them.

To review, the foods you want to stay away from are eggplants, tomatoes, tomatillos, potatoes, Goji berries, pimentos, ground cherries, bell peppers, chili peppers, paprika, cayenne, and the tobacco leaf.

You can read more about goji berries side effects to begin learning about these foods.

Do you think you can eliminate nightshades from your diet? If so, you could be doing a great service to your body by taking away constant discomfort. Give it a try. You’ll be glad you did.

Polyphenols aren’t just found in blueberries! They’re also found in Gundry MD’s groundbreaking polyphenol dark spot corrector.

Learn More:

15 Ways to Reduce Lectins in Your Diet

5 Delicious Lectin-Free Mexican Food Recipes

Sources 1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361210/ 2. https://www.britannica.com/plant/Solanaceae 3. https://www.sciencedaily.com/terms/alkaloid.htm 4. https://www.ncbi.nlm.nih.gov/pubmed/17153152 5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499388/ 6. https://www.sciencedirect.com/topics/medicine-and-dentistry/glycoalkaloid 7. https://www.ncbi.nlm.nih.gov/pubmed/8603093 8. https://www.ncbi.nlm.nih.gov/pubmed/15649828 9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569347/ 10. https://www.mdpi.com/1420-3049/23/3/644/htm 11. https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+3558 12. https://pubchem.ncbi.nlm.nih.gov/compound/alpha-Solanine#section=Toxicity 13. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1597169/ 14. https://www.ncbi.nlm.nih.gov/pubmed/504549 15. https://www.cfs.gov.hk/english/multimedia/multimedia_pub/multimedia_pub_fsf_112_01.html 16. https://www.ncbi.nlm.nih.gov/pubmed/12402311 17. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289646/#R25 18. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121179/ 19. https://www.ncbi.nlm.nih.gov/books/NBK310413/

4 Responses

  1. This is hardly a “comprehensive” list of nightshades. These are simply the five major nightshades found in American diet.

  2. I understand that squashes and peas are high in lectins and should not be consumed. I am accustomed to cooking the greenery from these plants. Are the leaves okay to eat?

Leave a Reply

Your email address will not be published. Required fields are marked *

Deals and offers
Make Gundry MD a part of your health and wellness lifestyle

Gut Health Starter Kit

Three of our bestselling gut-supporting Gundry MD formulas join together to create this digestion-boosting bundle.

Available for My Health Account members only!

Save Sticker

Save immediately with your free My Health account

Exclusive discounts, early access, free US shipping, Subscribe & Save!
Your Health magazine

Subscribe to Your Health magazine

Lectin-free recipes, health tips & tricks, and magazine-only discount codes!
Calendar Sticker

Save time & money with subscriptions

Choose items, choose frequency, enjoy savings!

You may also like

Some of our other customers liked these articles as well

Our most popular products

The Perfect Daily Pick-Me-Up

My Health Account Member Price $49.95

Regular Price $69.95

Member Price $49.95

The Ultimate Gut Guardian

My Health Account Member Price $49.95

Regular Price $69.95

Member Price $49.95

Supercharged Olive Oil For Optimal Wellness

My Health Account Member Price $39.95

Regular Price $49.95

Member Price $39.95

charity-water-logo-black
Health is a Human Right
Gundry MD is a proud sponsor of charity: water, a charity providing safe, clean drinking water to people in developing countries.
Join the Text Club
Sign up for exclusive access to major sales (up to 65% off), product releases & insider tips.

By texting GUNDRY to 51246, you agree to receive recurring automated promotional and personalized marketing text messages (e.g. cart reminders) from Gundry MD at the cell number used when signing up. Consent is not a condition of any purchase. Reply HELP for help and STOP to cancel. Msg frequency varies. Msg and data rates may apply. View Terms & Privacy.

Or text GUNDRY to 51246

Gundry MD logo mark
Save with a free My Health Account!

Updated Privacy Policy

We've revised our Privacy Policy pursuant to GDPR.
Please take a moment to review.

Search

My health account member Exclusive

Black Friday & Cyber Monday Sale

Sign up and get additional savings on your already-discounted My Health Account pricing.

$15 OFF $150+

Use code BFCM15OFF

$35 OFF $250+

Use code BFCM35OFF

$50 OFF $350+

free full sized Vital Recharge Use code BFCM50OFF

Excludes ambassador pricing. Limit 1 use per customer. Offer ends 12/2/24

EXCLUSIVE TO MY HEALTH ACCOUNT MEMBERS

Sitewide Holiday Sale

My Health Account members can save an additional 10% OFF already-discounted account pricing. Simply create your free My Health Account and enter coupon code HOLIDAYS10 at checkout.*

Save an additional 10% OFF your already-discounted My Health Account pricing. Use coupon code HOLIDAYS10 at checkout.*

*Only valid when logged into your free Gundry MD My Health Account. Excludes ambassador pricing. Limit 1 use per customer. Offer ends 12/13/24. Domestic orders must be placed by 12/13/24 to guarantee arriving by 12/25/24.

Discover Bio Complete 3 Today

Our all-in-one prebiotic, probiotic, and postbiotic formula to support better digestion, bowel movements, and energy.

Sign up for your My Health Account and get the best price + perks!

Save up to 60% off With a FREE My Health Account

My Health Account 60% Off Savings Unlocked!

Don't Miss Out!

Unlock

60% OFF

& Exclusive Perks!

Create a FREE My Health Account to enjoy:

Already have an account?

Login

You are already logged in

You can view your account or logout

New to Gundry MD?

Gundry MD, and the companies we work with, use cookies and other technologies to collect data to improve your experience on our site, analyze site usage, and facilitate advertising. By continuing to browse this site, you agree to our website Terms and Conditions and Privacy Policy.

Log in to Your Account

Get immediate deals on everything in our store and access to even lower prices with Subscribe & Save!

Don’t have an account?