Free US Shipping for orders $49+

[NEWS]: L-Arginine with L-Citrulline Helps Lower Blood Pressure

Although L-arginine supplementation has long been known to dilate blood vessels and lower blood pressure, a new study shows that a certain amino acid pairing can improve its effectivenesa.  Scientific research reveals that when you take L-citrulline together with L-arginine, it has a better absorption rate.

“Our data show for the first time that oral L-citrulline supplementation raises plasma L-arginine concentration and augments nitric-oxide metabolism-dependent signaling in a dose-dependent manner,” the researchers concluded.

In other words, when used in combination, the two amino acid supplements can help lower blood pressure.

The study examined 20 healthy, non-obese subjects including 13 males and seven females. “Diabetes, obesity, hypertension, cardiovascular disease, liver or kidney disease, current infections and smoking were exclusion criteria,” the authors reported. “None of the volunteers received any drugs that might alter amino acid or vitamin status, and dietary habits were kept constant during the study.”

The study was double-blind, randomized, and placebo-controlled – which is considered the gold standard practice in medical research. Subjects were given either L-citrulline .75 grams twice daily, L-citrulline 1.5 grams twice daily, L-citrulline 3 g twice daily, L-arginine immediate release 1.0 g, L-arginine sustained-release 1.6 grams twice daily or placebo for seven days.

“Oral supplementation with L-arginine has been used in a variety of clinical conditions, including (high cholesterol), coronary artery disease, congestive heart failure, peripheral artery disease, sickle cell disease, and in elderly humans, in attempts to improve nitric-oxide mediated vascular function,” according to the researchers.
“A recent small clinical study has suggested that oral L-citrulline may actually lead to higher elevations of plasma L-arginine concentrations than administrations of L-arginine itself,” they added.

Investigators independent of the study performed ultrasound and image analysis, in observer-blinded fashion, to measure the dilation of the arteries.


Leave a Reply

Your email address will not be published. Required fields are marked *

Deals and offers
Make Gundry MD a part of your health and wellness lifestyle

Gut Health Starter Kit

Three of our bestselling gut-supporting Gundry MD formulas join together to create this digestion-boosting bundle.

Available for My Health Account members only!

Save Sticker

Save immediately with your free My Health account

Exclusive discounts, early access, free US shipping, Subscribe & Save!
Your Health magazine

Subscribe to Your Health magazine

Lectin-free recipes, health tips & tricks, and magazine-only discount codes!
Calendar Sticker

Save time & money with subscriptions

Choose items, choose frequency, enjoy savings!

You may also like

Some of our other customers liked these articles as well

Our most popular products

The Ultimate Gut Guardian

My Health Account Member Price $49.95

Regular Price $69.95

Member Price $49.95

The Premier Gundry MD Prebiotic Blend

My Health Account Member Price $49.99

Regular Price $79.00

Member Price $49.99

Advanced Serum To Address Stubborn Discoloration

My Health Account Member Price $49.00

Regular Price $120.00

Member Price $49.00