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Polyphenol Reparative Serum contains a unique blend of the highest-grade natural ingredients, combined to give your skin a healthy, hydrated, “glowing” look. These powerful ingredients work together to defend against the most stubborn signs of aging by:

  • Giving skin a smoother, more even texture
  • Reducing the appearance of lines and creases
  • Supporting moisture retention and suppleness
  • Providing a softer, more satiny feel


This silky serum is designed to absorb quickly and deeply into skin, to deliver powerful revitalizing antioxidants right where they’re needed. By simply applying a dime-sized amount of Polyphenol Reparative Serum twice daily to clean, dry face and neck, you can begin feeling the potent restorative effects of polyphenols right away.

How did we make this formula so effective? We included several unique, concentrated sources of polyphenols, in precise amounts, combined to make one powerhouse serum:

Swertia Chirata Extract

SWT-7 is a complex extracted from a rare Himalayan root, helps to support skin’s natural strength and reduce the appearance of age-related lines

Oriental Tea Complex

Oriental Tea Complex is a unique blend of 6 Korean teas with antioxidant properties that assist in reducing the appearance of wrinkles

Plant Collagen Extract

Plant Collagen Extract comes from 5 different plants to help support skin’s natural moisture retention and provide radiance-boosting exfoliation

Red Grapevine Extract

Red Grapevine Extract provides unique nutrients that help give skin a tighter, more youthful look

Wild Yam Extract

Wild Yam Extract helps enhance skin’s radiance for a more “glowing” look


Gundry MD Dark Spot Diminisher is an easy-to-use serum that comes to you in a handy 1 oz. dropper bottle. Dispense a small amount (about the size of a dime), and apply directly to your dark spots.

As always, Gundry MD products use only the highest quality, purest ingredients


I take great pride in our products. We use only the best ingredients, and we proudly keep all of our manufacturing and customer service in the United States. We maintain the highest manufacturing standards in the industry, exceeding cGMP guidelines. As such, all of our products come with an industry-leading 90-day money-back guarantee. You can return your order for any reason. We will gladly refund your money, no questions asked. Your satisfaction is paramount to us.

Frequently Asked Questions


Anyone who struggles with wrinkles, fine lines, or other stubborn signs of aging can benefit from using Gundry MD’s Polyphenol Reparative Serum.

Our unique formula is designed to reduce the appearance of aging, while smoothing skin’s appearance for an overall younger, fresher look. Polyphenol Reparative Serum hydrates and deeply conditions, helping you revitalize your complexion and lessen the appearance of fine lines and wrinkles.


Polyphenol Reparative Serum takes a brand new approach to reducing the visible signs of aging, and helping you achieve a more youthful complexion:

Powerful polyphenols, found in natural plant extracts, help give skin an extra boost of protection against the environmental factors that can cause lines, wrinkles, and dullness. By infusing your skin with the antioxidants in this formula, you can get on the road to a smoother, more youthful complexion right at home!

We chose deeply nourishing, vitamin-rich natural extracts to help refresh skin’s appearance and provide a smooth, hydrated finish. By combining precise ingredients that help naturally reduce the appearance of lines and wrinkles, this formula offers a cutting-edge solution that can help you look (and feel!) younger, fresher, and more radiant.

Deep moisture is a key factor in a smooth, age-defying appearance. By providing skin with the hydration it needs to stay flexible, soft, and smooth, you can experience a renewed look and sense of pride in your complexion.


Apply a dime-sized amount of Polyphenol Reparative Serum twice daily to clean, dry face and neck. Lightly work into skin using upward circular motions to refresh and rejuvenate.


Polyphenol Reparative Serum was created with all skin types in mind. It is always best to perform a patch test before beginning regular use if you are concerned about using a new product. Simply apply a small amount of serum on an inconspicuous area (such as the inside of your arm) and leave it on for 24 hours to see how your skin reacts.


Polyphenol Reparative Serum is covered by our 90-Day Money Back Guarantee. If for any reason you don’t experience the results you’re looking for with Polyphenol Reparative Serum, contact our customer service team at (800) 852-0477 Monday-Friday, 5am to 7pm PST or Saturday-Sunday, 8am to 4:30 PM PST and we’ll refund your money, no questions asked. Our team is also happy to answer any questions you may have.


Deionized Water, Propanediol (Vegetable Sourced), Glycerin (Vegetable Sourced), Cetyl Alcohol, Polyglyceryl-3 Beeswax, Jojoba Esters, Polyglyceryl-6 Distearate, Dimethicone, Artemisia Princeps Leaf (Japanese Mugwort) Extract, Carthamus Tinctorius (Safflower) Seed Oil, Dimethiconol, Butylene Glycol, Chaenomeles Sinensis (Quince) Fruit Extract, Cinnamomum Cassia Bark Extract, Swertia Chirata Extract, Oxycoccus Palustris (Arctic Cranberry) Seed Oil, Chrysanthellum Indicum Extract, Camellia Sinensis Leaf Extract, Maltodextrin, Diospyros Kaki (Persimmon) Leaf Extract, Argania Spinosa (Argan) Kernel Oil, Chenopodium Quinoa Seed Extract, Daucus Carota Sativa (Carrot) Root Extract, Dioscorea Villosa (Wild Yam) Root Extract, Glycine Max (Soybean) Seed Extract, Vitis Vinifera (Grape) Seed Oil, Hexapeptide-11, Rhodiola Rosea (Roseroot) Extract, Sclerotium Gum, Sodium Hyaluronate, Vitis Vinifera (Red Grapevine) Extract, Lysolecithin, Oryza Sativa (Rice) Extract, Panax Ginseng Root Extract, Pullulan, Polymethylsilsequioxane, Allantoin, Xanthan Gum, Carbomer, Caprylhydroxamic Acid, Caprylyl Glycol, Ethylhexylglycerin, Fragrance (Parfum), Aminomethyl Propanol


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Good Stuff
Customer: Kathy

Helping smooth out wrinkles
smoother appearance
reducing age spots

Customer: Mary Ann

I have been using the Polyphenol Reparative Serum along with the Polyphenol Correct and Calm and the Firm & Sculpt for almost a month. My niece told me how much she liked it, as we are both on all the other products. Because I have used a natural skin care for years and love it, I was reluctant to change. I already let her know how much better I like these. The Serum is not greasy in any way and feels so good on the skin. Along with the other two they have have such a refreshing feel and my skin is so soft. BTW I am in my 70s and people are always surprised when I tell them my age. I try to keep the wrinkles at bay. Also, it is helping to heal a red spot on my nose that is almost skin pink now. Love this line very much. Penny was right Dr. Gundry as you needed to develop a skin care. Thanks much.

Customer: Daniel

I have been using the serum for about a month and I must say I really like it. I received a sample tube of the serum and tried it and was amazed how my skin felt and looked after applying the serum. My face felt cleaner, smoother, and more virbrant so I look forward to continuing to use this product.

Excellent Skin Care Products
Customer: TJ

I have been using the skin care products for two months. Love them. Using Spot Diminisher, Probiotic cream, Firm sculpt cream and polyphenol reparative serum. I am a very outdoors active person who has a lot of sun damage, laugh lines, and dry skin. My face and neck are finally getting some well deserved attention from these wonderful great products. My skin is smooth, smaller pores, more even in color, age spots diminished and feels good when I smile. Do not want to lose all of my smile lines though.

Customer: Rosalind

I love the skincare line, and Iyani, the representative who helped me today with an order, was awesome!

Wonderful Product, Worth Every Penney
Customer: Doni Zahn

I love the Gundry skin care line, and this product is no exception. I have had numerous comments about how good my complexion looks and that I appear to have less wrinkles. I have never spared money on quality skin products, and these products are better than anything I've ever used. You will not be sorry about this purchase. I also use the Firm and Sculpt during the day and the Correct and Calm at night. Love them all.

Amazing value and Glowing skin
Customer: Sue Tsigaros

I am amazed how effective this serum is! After only 10 days of use I am noticing the lifting effect, my skin is smoother, softer and very well hydrated. I am using much less of my regular creams by simply replacing my other (more expensive) serums with this serum. It is a great value product in itself and is also saving me money on other products. I also use Vital Reds and Primal Plants and the overall effect on my skin is - glowing!

Softer and Smoother
Customer: Jeni Ford

Absolutely love this product. I’m 63 yrs young.
My skin was damaged from over waxing and sun damage.
I purchased the Reparative Serum and from day 3 started to notice a big difference...... after 2 weeks the skin was softer smoother and looked healthier ‼️
I’m now combining it with the Polyphenol Correct and Calm and the Firm and Sculpt with added amazing results.
My lines have softened , the skin is radiant so my daughter says....... thank you Dr Gundry.

This serum is terrific!
Customer: Paula Stern

I just ordered my second vial of this and use it along with the Gundry firming cream. I notice a visible difference in the firmness of my jawline and a healthy glow to my skin. Great products!

Repairative Serum
Customer: Christine McClure

I really like this serum. It goes on so light and absorbs very well. I would highly recommend it. My face is so soft but not greasy after I put it on and it doesn't take much at all.

Customer: Tata

Love this product! Since I began using it my skin feels softer.

Customer: Sherry

I will be reorder this. It is helping those small unwanted lines. Thank you Dr. Gundry for the help in making feel and look younger.

Customer: Maylin B Ashe

I am amazed at the results I have gotten from Polyphenol Reparative Serum! The combination of it and 4 other products from GundryMD has been over the top in pleasing me. I do not give this kind of praise to many things I get, but this truly was worth the time it took to talk about these products. Try them. You won't believe it. I must say that healthy eating has to go along with them, though. I am on a campaign about that because it is what we all need the most.

Customer: Linda Heimueller

I am so impressed with all the products I have brought. You see and feel the difference so fast. Best I can say you should be very proud of your research, work and I see and feel the difference. Thank you

I love this Serum!!
Customer: Leni Nimsgern

I love this Serum!!! It makes my face just glow!!?I also use the moisturizer, When I wake up in the morning my face feels so smooth and hydrated, never oily!!!

Incredible product
Customer: Debra Covington

I look forward to each time I get to use my Reparative Serum. It feels so good on my skin and my skin gets softer and smoother each time. I cant help but touch my skin to feel what I see in the mirror, which is healthier and more vibrant skin. My wrinkles continue to diminish! Thank you for this wonderful product! I am sold on all of your products!

Repareative serum
Customer: Gail Sachs

Love this product! Since I began using it in the morning and evenings, my skin feels softer and seems to be clearer.

Customer: Candi

I have been using the product for about a month. I like it and feel it does a good job

glowing skin
Customer: Natalie Pace

I receive many compliments on my appearance since using this product for a couple of months. Younger, brighter, and full of vitality are the remarks I hear. I notice a reduction of fine lines and and softer features. I feel as though I am glowing much of the time

Silky smooth skin
Customer: Morgan

Love the silky texture that melts right into my skin, just a tiny amount and I can feel it revitalizing my face and neck. My skin feels nourished not just moisturized!
Smells wonderful too. I can't wait for a "sister product"?!

* Every individual is unique. As such, your results can and will vary.


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5 out of 5 stars
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5 based on 20 votes GundryMD Polyphenol Reparative Serum
USD 120.00 Available in Stock