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I created Heart Defense to support your heart’s ability to deliver nutrients and oxygen throughout your body. Healthy circulation helps your body naturally revitalize itself… the key to looking and feeling younger.

Heart Defense can help you:

  • Supports nitric oxide levels, the key to a healthy, younger-feeling you
  • Fight off unhealthy cravings
  • Improve focus and mental sharpness all day
  • Naturally boost energy without crashing


We work hard every day to deliver the most advanced, cutting-edge formulas on the market today, and I want to personally say: I’m proud of every single one of our formulas. Our 90-day guarantee is designed to allow you to achieve optimal results from your products, risk and worry free.

Frequently Asked Questions

How safe is Gundry MD Heart Defense?

Gundry MD Heart Defense contains only 100% natural and safe ingredients. The formula is tested for quality and purity at an independent, 3rd-party facility. However, I recommend consulting with your own health care provider before beginning any new program.

How do I use Heart Defense?

Simply mix one scoop of this powder into a beverage of your choice — water, milk, etc. — and it’s ready to go. Drink just one glass a day on a consistent basis. The formula digests easily, so you can take it with or without a meal, whenever you’d like.

How does Gundry MD Heart Defense work?

Heart Defense works by utilizing flavanols in the high-grade cocoa power and flavonoids in the patented coffee fruit extract to help “boost” your body’s own nitric oxide production process.  Nitric oxide levels are linked with healthy circulation levels, and you should be able to feel the powerful benefits throughout your entire body. Prebiotic fiber and omega-3 have been added to enhance absorption and heart health benefits.

When can I expect results?

Most users report feeling a noticeable increase in energy and vitality on their first day of use… usually within the first hour. However, the most dramatic results were reported after consistent use over the course of 4 weeks and beyond. Please use as directed.

What are the ingredients in Gundry MD Heart Defense?

What if it doesn’t work for me? Is there a guarantee?

As a physician, I know that individual bodies can react differently to the very same compounds. Even though everyone can benefit from the flavonoids, flavanols, and prebiotics in this formula, I’m aware that results can vary. So, if you’re unsatisfied with this product for any reason whatsoever after a full 90 days of use, I’ll return your money, hassle-free… guaranteed.

Does Heart Defense contain caffeine?

Heart Defense does contain a trace amount of caffeine — only 2 mg per serving. To give you an idea of how little this is, DECAFFEINATED coffee contains between 8 and 14 mg of caffeine per serving.


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Customer: Brian

I love the way this tastes along with the Vital Reds.

great products
Customer: marie

have been using prebiothrive then added vital reds and now heart defence.feeling refreshed sleeping much better, more energy,less bad cravings. thank you Dr G

Customer: Marilyn

Got it for my husband. The last appointment with heart Dr was great. No other medication just the drinks with this and vida reds and plant defense

Heart Defence
Customer: Anthony Howden

Up at 4am heart defence gets me through to mid morning. Great product

Gundry Products
Customer: Caroline

I started out with Vital Reds and was so pleased with the results. The last two to add are Prebio Thrive and Heart Defense. I am very glad I purchased them! The Heart Defense has been very helpful with function of my heart. Has decreased issues tremendously! Each of the products are well worth taking!!!

Customer: Colleen

I love heart defense.. I drink it while on my morning walk. Tastes good and gives me energy!

Customer: Dana Jae Labrecque

I have never found a better way to get through a long day of teaching. I take one scoop of this in water in my office between classes that I teach and it's like I've just been totally refreshed AND my appetite is perfectly suppressed as well. I have been a huge fan of Vital Reds for a year with the addition of Prebio Thrive in the past 3-months. THIS ONE is definitely on my forever daily list.

Excellent Product
Customer: Cris

I really like the product and drink it every morning. It has definitely made a difference in the way I feel.

I'm impressed!

Great taste & Healthy
Customer: James

I mix a scoop each of Heart Defense, Vital Reds, and PrebioThrive as my breakfast. Rich tasting and a great start to the day.

Heart Defense
Customer: Lisa Lingoni

I feel great since I've been taking the Heart Defense. I no longer need to drink coffee. I get up in the morning and I'm good all day.It's amazing!

Customer: Gene

Heart Defense has made a HUGE difference in my blood pressure for the better and so much more! Add to this, I've quit drinking coffee which made even more of a difference. My gym work outs are so much age 63! And like other reviewers have said, I should have ordered the three pack when I had the chance. But no matter, will continue taking Heart Defense from here forward. Thank you Gundry Team!

Heart Defense Awesome
Customer: Usero

I have been taking Heart Defense together with Primal Plants and Prebio for a week now and it is great. All day long without dragging. Glad I ordered the Hearts Defense. It's a whole world of energy. Sleeping good at night and waking up in the morning ready to tackle the day. I love it.


Customer: patricia rew

Heart Defense has renewed my energy level and focus and I'm sleeping so much better. I wish I had ordered the three pack to take advantage of the great savings. My mistake. Pat

Heart Defense & Prebio Thrive
Customer: Blaise

On top of our refrigerator I have both supplements- I take Prebio Thrive in the am and Heart Defense later in the day. I’m grateful for the products and research! Thank you Dr. Gundry🏅👨‍⚕️🎖

primal greens & Vital reds
Customer: laura griffith

I don't often drink enough water in the course of a day. This wonderful, well researched product makes it easy. Every day at work I make it a point to consume a scoop in 16 oz of water or green cold tea.
Bravo Dr. Gundry and thank you

Exceedingly pleased with the product & Plant Paradoc Protocol book!
Customer: Anne

Top notch!

Enhanced energy flow and aliveness
Customer: Annine Massari

I mix Dr. Gundry Heart Defense with a scoop of the vital Reds every morning and it is frickin amazing. I could feel the energizing effects within the first 3 days of use. It is a staple for me now! Bless and Thank you Dr Gundry!’

Pleased with results from Heart Defense
Customer: Bonnie Wheatley

I noticed that I immediately started sleeping better the first night after I started taking Heart Defense. This has been a wonderful benefit for me and adds to my energy and vitality for the day.

Heart defense
Customer: Karen Cooper

I feel really good but am also taking vital reds and prebiothrive. I think they all are helping.

Heart Defense
Customer: Tom Heflin

I have been using this formula for about a year. Instead of having coffee in the morning I put a serving of Heart Defense in a cup of hot water and add a touch of non dairy creamer and drink this delicious mixture before jogging and weight lifting. I am 83 and have never felt better.

* Every individual is unique. As such, your results can and will vary.


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5 out of 5 stars
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5 based on 20 votes GundryMD Heart Defense
USD 85.95 Available in Stock